Fertility Drugs for Women

Clomiphene Citrate is a fertility drug that helps induce ovulation and helps in fertility for women. It aids the body by tricking it that it needs more estrogen in the body. Thus it stimulates it into producing follicle stimulating hormones (FSH) as well as leutinizing hormones (LH).

This drug is available in 50 milligram tablets. For the dosage range, it ranges from 25 milligrams to 150 milligrams – ½ tablets to three tablets, respectively. It has to be taken once a day for five days in a woman’s menstrual cycle.

Here are the side effects experienced when taking the drug: hot flashes, ovarian enlargement, nausea, vomiting, enlargement of the breast, multiple pregnancy, disturbance in vision, and headaches.

Human menopausal gonadotropin (Pergonal, Humegon, Repronex)

Also known as hMG, it is a medication comprised of follicle stimulating hormones, whether it has leutenizing hormones or none at all. It helps in the stimulation of the eggs in the woman who experiences infrequent ovulation. It also helps those women who have irregular ovulation.

Human menopausal gonadtropin is available as an injectible. So women who needs this type of drug are taught on how to perform subcutaneous and intramuscular injecting techniques. The injection should only be done at around 6 to 10 in the evening only.

The known side effects for this type of drug are: hyperstimulation syndrome, multiple gestation, breast enlargement, headache, and abdominal pain. Discomfort may also be experienced in the part of the body where the injecting was performed. Having it monitored by ultrasound and estradiol may lessen the risk of complications.

Human chorionic gonadtropin (Profasi, Pregnyl)

This is a natural hormone that aids in the maturation of the eggs, leading them to the stage where the ovaries will let out eggs that have reached the point of maturity. It also helps in simulating the corpus luteum. This allows the secretion of progesterone that is essential for the preparation of the lining of the uterus for egg implantation.

Similar to the hMG, it is available as an injectible and is performed through intramuscular means. Here are the known side effects for hCG: irritability, headaches, depression, restlessness, fatigue, edema, and ovarian hyperstimulation.

Leuporide and synthetic gonadotropin inhibitor (Lupron and FSH/LH, respectively)

Lupron represses the brain to secrete more leutenizing hormones as well as follicle stimulating hormones. This is used in the preparation for the treatment along with the drugs that inducts ovulation.

It also inhibits the growth of a dominant follicle upon the coming menstrual cycle but allows follicle recruitment. It helps in the prevention of premature ovulation since it suppresses the release of LH.

An ultrasound can be performed before the stimulation of the ovaries to know if the effects of Lupron is found to be effective. A test for the level of blood estrogen may also be required in this matter. It may even be more effective if used early in the menstrual cycle.

This is available as an injectible and is performed using a subcutaneous technique. It has to be kept in a cool temperature like 75 degrees Fahrenheit, therefore, it has to be refrigerated. It has to be taken at a similar time it was taken with a leeway of one hour. For those who have experienced consecutive menstrual cycles, they have to use barrier contraception on preparation for the cycle.

The side effects for this drug are known to be the following: dryness of the vagina, skin rash, and hot flushes. Also, using this for about six weeks may include long-term side effects like bone loss. However, cases like these are uncommon upon short-term use.


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